Budding Yeast: Saccharomyces cerevisiae

Saccharomyces cerevisiae, the budding yeast, is the common yeast used in baking ("baker's yeast") and brewing ("brewer's yeast"). (It is only distantly related to another unicellular fungus, Schizosaccharomyces pombe, the fission yeast.)

It is a popular "model" organism in the laboratory because it is a unicellular eukaryote whose cellular activities are much more like ours than those of a bacterium like E. coli. But like E. coli,

Life Cycle

Budding yeast can live with either two genomes (diploid, n=32)) or one (haploid, n=16). In either case, it reproduces by forming buds (hence the name) by mitosis.

Haploid cells occur in two different mating types: a or α. The type is determined by the expression of a gene at an active mating type locus.

Haploid cells can live indefinitely in the haploid condition. However, if two cells of opposite mating types meet, they can fuse and enter the diploid phase of the cell cycle.

This is not as rare event as you might expect.

Cells in the diploid phase are more resistant to harsh environmental conditions. When diploid cells begin to run out of food, they undergo meiosis, forming four haploid spores in an ascus (Saccharomyces cerevisiae belongs to the ascomycetes.)

When good conditions return, the spores germinate producing four haploid yeast cells: two a and two α.

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6 June 2014